Accutane (isotretinoin) 40 mg is a powerful medication used to treat severe acne that hasn't responded to other treatments. To take Accutane 40 mg, it is usually prescribed as a once-daily oral capsule, taken with a full glass of water. It's important to take it with food, as this increases the absorption of the medication into your body. Accutane can be harsh on the stomach, so avoid lying down for at least 10 minutes after taking it. Dosage and duration depend on the individual's condition and response to treatment, and it's crucial to follow your healthcare provider’s instructions carefully. Since Accutane can cause serious side effects, including birth defects, regular follow-ups, blood tests, and strict adherence to contraception for women of childbearing age are mandatory.